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Aerobic capacity and physical functioning in children, adolescents, and young adults with brain tumour and the benefits of exercise in this specific population. A systematic review.

(2020)

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Mesureur_Yoline_51851600Pirard_Audrey_27251600_2019-2020.pdf
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Abstract
Context: Children, adolescents and young adults treated for central nervous system tumour are at increased risk to develop late effects which lead to functional limitations. As they have many impairments, their engagement in physical exercise is impacted. Objective: The aim of this systematic review is to present an up-to-date investigation about physical activity in children, adolescents and young adults with brain tumour and the benefits of an exercise intervention in this population. Methods: A comprehensive search equation was inserted in the five databases (PubMed, Cochrane, Embase, Sciencedirect, Scopus). RCT, Non-RCT and observational studies published in English since 2010 and matching PICOS criteria were included. PRISMA guidelines were followed to ensure a high scientific rigor. Results: Only 14 studies out of 1082 articles were included. The quality of the studies was overall fair. Lower levels of physical activity were observed in this population. Exercise interventions showed positive gains on several variables: cardiorespiratory fitness, physical functioning, cognitive outcomes, and quality of life. Preliminary evidence was found regarding benefits of exercise on the brain volume. Conclusion: Globaly this population has impairments in several fields due to treatments or the tumour itself. Regular moderate exercise is beneficial for these young patients. Future high-quality research with larger sample size are needed to confirm these results.