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Optimisation of the microfluidic system of Dolomite for nanoparticle production

Carbon, Arthur
(2024)

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Details

Supervisors
des Rieux, Anne ; Dupont-Gillain, Christine C.
Faculty
Faculté des bioingénieurs
Degree label
Master [120] : bioingénieur en sciences et technologies de l'environnement, à finalité spécialisée
Abstract
In the current effort to enhance medical practices and drug delivery, optimizing the production of nanoparticles for medical applications is crucial. In the ADDB research laboratory at UCLouvain, a new microfluidic system has been purchased from the compagny Dolomite to produce nanoparticles. This system is more innovative than the conventional method and is therefore more promising. The aim of this master thesis is to use this new device for the first time in order to understand how it works and thus obtain nanoparticles that are more suitable for medical applications and for industrialisation. In the long term, the idea would be to generate a predictive model based on this microfluidic system capable of producing nanoparticles adapted to a certain use. Numerous experiments have been carried out with the aim of producing nanoparticles, studying the impact of changing system variables on the nanoparticles and making a first attempt to produce a predictive model. These experiments are presented in this master thesis.