Cold evoked potentials : charachterization of the normal values for healthy subjects

Details

Supervisors

Mouraux, André

Faculty

Faculté des sciences de la motricité

Degree label

Master [60] en kinésithérapie et réadaptation

Abstract

Objective: The aim of this study was to determine if evoked potentials elicited by a very fast cooling of the skin could be reliably obtained from healthy subjects, to determine their characteristics (latency, amplitude, topographies) and to assess in what way experimental factors (Δ temperature, slope and stimulation surface) affect these characteristics. Method : Experiment 1: 20 subjects, goal temperature: 10°C, slope: -300°C/s, surface: 42 vs 125mm² Experiment 2: 21 subjects, Δ temperature: -5°C vs -10°C vs -15°C vs -20°C from basal skin temperature, slope: -133°C/s vs -200°C, surface: 125mm² Stimuli were applied on the central third of the volar forearm. EEG was recorded using a 32 channels electrode cap using the 10-20 international system. A rating of the intensity of the cold sensation elicited was asked to the subjects for every or certain stimulations (depending of the experiment). Results : Clear EPs very similar to laser-evoked potentials (LEPs) were obtained for every trial. An effect of the stimulation surface was shown on the behavioural ratings, the latency of the N2 component and the amplitude of the N2P2 complex. An effect of the Δ temperature was shown on the behavioural ratings and (potentially) the latency of N1 peak. An effect of the cooling slope was shown on the amplitude of P2 peak. Conclusion : The study of CEP’s is a very promising method for both clinic and research.

Citations

• APA

Courtin, A. (2017). Cold evoked potentials : charachterization of the normal values for healthy subjects.