Prévalence de l’hypercalciurie et ses causes dans une cohorte de patients lithiasiques suivis aux CUSL entre 2017 et 2018
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- Hypercalciuria is an abnormally excessive amount of calcium in the urine. There are two types : flow hypercalciuria which is defined by 24h-calciuria ≥ 0.1mmol/kg/24h and ≥7.5 mmol/24h (i.e. 300 mg/d in men), ≥6.25 mmol/24h (i.e. 250 mg/d in women); concentration hypercalciuria which is calciuria ≥3.8 mmol/l. It is the most common metabolic abnormality seen in patients with nephrolithiasis. Indeed, data from the literature report that in 40 to 75% of cases the metabolic abnormality found corresponds to hypercalciuria. The main causes of hypercalciuria are dietary errors (excessive sodium intake, excessive protein intake), primary hyperparathyroidism and idiopathic hypercalciuria. Hypercalciuria can be associated with various complications, namely renal lithiasis disease mainly, altered bone mineralization, medullary nephrocalcinosis as well as chronic renal failure. Due to all the complications mentioned above related to hypercalciuria, we carried out this study in order to determine what is the prevalence and what are the factors responsible for hypercalciuria in a cohort of 185 lithiasis patients followed at the Saint-Luc clinics in the nephrology department between 2017 and 2018 and compare them with data in the literature.