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What are the non-localized effects of the blood flow restriction training: a Scoping Review

(2024)

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Abstract
BACKGROUND: The BFR training has been stated as a safe strengthening technique used and a safe rehabilitation tool if it's properly applied but to the best of our knowledge, there are only some articles that reported the non-localized chronic adaptations of BFR training. The main objective of this scoping review is to assess the current literature on the non-localized effects of chronic use of the BFR technique. Secondly, this review will identify gaps in the existing research that could be addressed in future studies. METHODS: The search equations were entered into three scientific databases: Embase, PubMed, and Scopus. The "Grey literature" was screened by searching on Google Scholar and through several websites. The studies had to meet the eligibility criteria to be included. The scoping review was drafted following the PRISMA guidelines. RESULTS: A total of 56 articles were included in this exploratory review following the selection process. The results show a trend towards improvement in anaerobic and aerobic capacities, mainly for VO2max and PPO. Adaptations were also observed for certain measures of body composition, such as percentage of fat mass and lean mass, as well as for certain blood homeostasis data: glucose levels, cholesterol (total and LDL-C), eGFR and triglycerides. Finally, neuromuscular effects were also observed in the EMG amplitude. Few and some conflicting results were found for BFR's cross-transfer effect, either in proximal cuff muscles or unrestricted limbs. CONCLUSION: The use of BFR seems to lead to non-localized effects. However, further research is needed to confirm some of these effects. In the future, these non-localized effects could be advantageous in the management of pathological populations such as patients with chronic kidney disease, chronic heart failure or obesity.