ATTENTION/WARNING - NE PAS DÉPOSER ICI/DO NOT SUBMIT HERE

Ceci est la version de TEST de DIAL.mem. Veuillez ne pas soumettre votre mémoire sur ce site mais bien à l'URL suivante: 'https://thesis.dial.uclouvain.be'.
This is the TEST version of DIAL.mem. Please use the following URL to submit your master thesis: 'https://thesis.dial.uclouvain.be'.
 

Bioreactor including electrical and mechanical stimulation for a monoaxial muscle

Rouvez, Alice
(2018)

Files

Rouvez_44121200_2018.pdf
  • UCLouvain restricted access
  • Adobe PDF
  • 116.22 MB

Details

Supervisors
Herman, Benoît ; Kerckhofs, Greet
Faculty
Ecole polytechnique de Louvain
Degree label
Master [120] : ingénieur civil biomédical
Abstract
This thesis presents the design, assembly and test of a bioreactor for a monoaxial muscle, that includes both electrical and mechanical stimulation. A first version of this bioreactor was designed last year (2017) but several remaining issues prevent its proper functioning. Therefore, the transmission and the chamber designs were changed to ensure a biocompatible, airtight, and sterilizable bioreactor, with an easy mounting, and a functional stimulation. The new design showed great results with regard to the sealing and the mounting of the bioreactor, but a new membrane with less rigidity should be found to ensure the actuator shaft sealing. The different implemented stimulation modes were tested first with springs and weight, and afterward on a pork abdominal muscle, showing good results as well. Even if further investigations should be done regarding the filtering of the force measurements, this bioreactor have already brought a lot of improvements.