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Tubulointerstitial infiltration by adaptive immune effectors in ANCA-associated glomerulonephritis

Jagannath, Modini
(2020)

Files

Jagannath_Modini_72311300_2019-2020.pdf
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  • Adobe PDF
  • 6.75 MB

Details

Supervisors
Lauwerys, Bernard
Faculty
Faculté de médecine et médecine dentaire
Degree label
Master [180] en médecine
Abstract
This retrospective study analyzes the presence of tubulointerstitial infiltration by interstitial fibrosis and adaptative immune effectors (T and B lymphocytes) in diagnostic biopsies of ANCA-GN. Our purpose is to provide a detailed characterization of the infiltration and to determine whether it is associated with long-term renal outcomes. Tubulointerstitial infiltration at diagnosis could serve as a marker to define a prognosis for ANCA-GN if a correlation with the severity of the pathology is established.