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Reliability and measurement error of exercise-induced hypoalgesia in healthy adults and adults with musculoskeletal pain: a systematic review.

Aron, Vladimir
(2022)

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Aron_Vladimir_97361600_2021-2022.pdf
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Details

Supervisors
Pitance, Laurent ; Armijo-Olivo, Susan
Faculty
Faculté des sciences de la motricité
Degree label
Master [120] en sciences de la motricité, orientation générale, à finalité approfondie
Abstract
Background. We systematically reviewed the reliability and measurement error of Exercise-Induced Hypoalgesia (EIH) in healthy adults and in adults with musculoskeletal (MSK) pain. Methods. We searched EMBASE, PUBMED, SCOPUS, CINAHL, and PSYCINFO from inception to the 20th of November 2021. The inclusion criteria for studies were the involvement of adults with or without MSK pain, the combined use of a single bout of exercise (any type) and an experimental pain test, and the assessment of the reliability and/or measurement error of EIH. Two independent reviewers selected the studies, assessed their Risk of Bias (RoB) with the COSMIN RoB tool, and graded the individual results (COSMIN modified GRADE approach). Results. We included five studies, conducted on healthy subjects (n = 168), and deemed to have an overall “Doubtful” RoB. The following ranges of parameters were reported: intraclass correlation coefficients, 0 to 0.61; kappa, 0.01 to 0.46, standard error of measurements, 30.1 kilopascal (kPa) to 105 kPa and 10.4% to 21%; smallest detectable changes, 83.54 kPa to 291.05 kPa and 28.83 % to 58.21 %. Discussion. The reliability and measurement error of EIH were respectively rated, with a very low level of certainty, “insufficient” and “indeterminate”. The evidence was limited by its “Doubtful” RoB. Future studies could consider using standardized exercises, other test modalities than pressure pain threshold, rater/assessor blinding, and strict control of the sources of variations.