The influence of cannabinoid CB1 receptor (CB1R) on dopamine D2 receptor (D2R) conformation and signaling mediated by agonists used in the treatment of Parkinson's disease
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Qyrsaqi_Valeria_24621700_2022-2023.pdf
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- Abstract
- The aim of this project is to evaluate the influence of the CB1R on the D2R focusing on D2R conformational changes, CB1R-D2R heterodimerization and effector recruitment (Gαi protein and β-arrestin2).